One in every nine women in the UK will develop breast cancer at some point in her life - more than 45,000 cases are diagnosed each year. It has become the most common cancer in the UK, and is the leading cause of death for women aged 34 to 54.
Men can also develop this cancer.
Despite recent improvements due to better treatments and earlier detection, the UK still has one of the highest mortality rates for breast cancer in the world. But research is beginning to reap dividends in new ways of understanding how breast cancer cells work.
Breast cancer is a disease in which malignant (cancer) cells form in the tissues of the breast. Damage to the DNA of these cells results in uncontrolled cell division and growth, and, eventually, sufficient cells accumulate to form a lump.
The cells invade normal surrounding breast tissue and can break off from the primary lump to spread in lymph channels or the blood stream to other organs where secondary lumps (metastases) may form.
The breast is divided into ducts and lobules. The most common form of breast cancer arises from the ducts and is known as invasive ductal carcinoma. Cancers arising from the lobules (invasive lobular carcinomas) are less common.
As with most cancers, the key to successful treatment is early diagnosis before the cancer has had the chance to spread to other organs.
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